Born in Providence, Rhode Island, Don Lapre moved to Phoenix, Arizona with his family when he was a child. He married Sally Redondo in 1988. A high-school dropout, in 1990, Lapre and his wife started a credit repair business called Unknown Concepts. Lapre then began selling a 36-page booklet explaining how to recover a Federal Housing Administration insurance refund after paying off a home mortgage. He also began offering “900” phone lines. On TV infomercials in the early–mid 1990s, he claimed that by placing “tiny classified ads” in newspapers he was “able to make $50,000 a week from [his] tiny one-bedroom apartment”. In 1992, Don Lapre began broadcasting The Making Money Show with Don Lapre, which suggested that viewers could make money as easily as he had. For several years the show was ranked among the ten most frequently broadcast cable television infomercials. The principal product was Lapre’s “Money Making Secrets”, a package of booklets, tapes, and common-sense tips for placing ads and operating a 900-number business. The product was sold through “New Strategies”, whose parent company was Tropical Beaches. In 2005, the Food and Drug Administration (FDA) warned Lapre about claims his vitamins were intended as a drug for diseases such as diabetes, stroke, heart disease, insomnia, cancer, and arthritis. The FDA stated “Your products are not generally recognized as safe and effective for the above referenced conditions.” In 2006 the FDA again warned Lapre about untruthful claims.

According to a June 15, 2011, Associated Press article, Don Lapre was indicted by a federal grand jury in Phoenix, Arizona, on June 8, 2011, on accusations of running a nationwide scheme to sell worthless Internet businesses. Federal prosecutors accused Lapre of bilking more than 220,000 victims out of nearly $52 million. He was charged with 41 counts of conspiracy, mail fraud, wire fraud, promotional money laundering, and transactional money laundering. A federal judge issued a bench warrant for Lapre on June 22, 2011, after he failed to appear at his arraignment. On June 27, 2011, Lapre was arrested in Tempe, Arizona, at a Life Time Fitness center, where he had reportedly lived for two days, with serious self-inflicted knife wounds to his groin. The wounds led authorities to believe Lapre had attempted suicide while at the Lifetime Fitness by attempting to sever the femoral artery in his legs. Don Lapre died in custody from an apparent suicide on October 2, 2011, while in jail awaiting his trial, which was scheduled to begin on October 4, 2011. Lapre died from severe blood loss after cutting his throat with a razor blade. The autopsy report stated that Lapre died of massive blood loss and had wrapped himself in sheets to conceal any blood loss from prison officials.